DETECTION OF TRICLOSAN ON GOLD NANOPARTICLES MODIFIED SCREEN-PRINTED CARBON ELECTRODE (AuNPs-SPCE) IN PERSONAL CARE PRODUCT

Abstract

Triclosan (TCS), a bactericide, has been identified as an endocrine-disrupting chemical (EDC) that can disrupt thyroid hormones and cause diseases such as hyperthyroidism and thyroiditis. This study evaluated the electroanalytical performance of a gold nanoparticle-modified screen-printed carbon electrode (AuNP-SPCE) for TCS detection. The primary goal of this study was to detect TCS in personal care products (shower gels) using AuNP-SPCE. The electrochemical performance was evaluated in potassium ferrocyanide, K₄Fe(CN)₆ (5 mM), standard TCS in 0.1 M PBS (pH 7), and shower gel samples using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The AuNP-modified SPCE (AuNP-SPCE) showed reversible electrochemical oxidation and reduction. TCS detection occurred at -0.02 V, focusing on the oxidation peak of the TCS curve. The calibration graph was linear from 2.1 to 10 mM, with a correlation coefficient (R²) of 0.999, and the detection limit was 0.89 mM. Scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX) characterized the AuNP-SPCE. Additionally, the AuNP-SPCE exhibited excellent stability over repeated use, indicating its robustness and potential for practical deployment in real-world settings. Such attributes underscore the sensor’s capability to deliver consistent and accurate results, reinforcing its value in applications demanding sensitive and stable detection platforms.